This is a fantastic game to go into without any guidance. As long as you aren't playing at too high a difficulty it's very accessible and straightforward.
That being said: read the prompts. You'll be given tips throughout the game, and even when there isn't a hint the dialogue is pretty funny.
If you can't find the objective of a quest you can go to the quest menu and select "remember description" to review the quest introduction.
If you find yourself taking damage but aren't near an enemy or inflicted with any status effect highlight the spoiler below.
Note: this does not apply to the tutorial